Light micrograph of skeletal muscle cells showing cytoplasm and nuclei

This pulsating muscle graft mimics benefits of exercise

Mice with the surgical implant developed more muscle mass, strength and bone density.

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  • A robotic, cell–free platform rapidly prototypes redesigned genetic codes, enabling the translation of proteins with reassigned codons and non-standard amino acids without altering living genomes.

    • Felix Radford
    • Nayan Sapers
    • George M. Church
    ArticleOpen Access
  • Malva enables ultrafast, reference-free searching of raw single-cell sequences across millions of cells, transforming static transcriptomic atlases into dynamic resources for understanding the functions of sequences.

    • Daniel León-Periñán
    • Nikos Karaiskos
    • Nikolaus Rajewsky
    ArticleOpen Access
  • Restudy of a challenging fossil using cross-polarized light imaging and phylogenetic reconstruction identifies Chosha praecursor, a probable early-diverging insect, helping to bridge the longstanding ‘hexapod gap’ in the fossil record.

    • Erik Tihelka
    • Carlos Vásquez
    • Chenyang Cai
    Article
Microscope image of engineered RNA nanostars

Nanoscience and nanotechnology

From programmable RNA architectures to next-generation materials for energy and health care, researchers are harnessing the unusual properties of the nanoscale to tackle some of society’s biggest challenges.
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