If you do switch back to Linux I’ll note that Endeavour and other Arch forks have moved away from older NVIDIA cards because NVIDIA stopped supporting open source drivers. There’s community-maintained solutions out there though. I forget exactly how old, but my 1080 got the boot, and then I had to gety Grover’s from AUR for a bit, right before that security breach. That contributed to my decision to upgrade to a new AMD card.
Holy shit, are you me?
One minor update I have from this experience, after building a new rig and restoring from a backup of the original system, I tried plugging in my SSD to my new computer and it isn’t even recognized in BIOS. I was under the impression my drive failed.
Me and two friends were coincidentally summoned at the same time - 3 different counties across two states. Mine and one of my friend’s summons were cancelled, and my other friend just got sent home yesterday from a case as he wasn’t needed. But the position has tenure for 3-4 months so we might have to go back.
PIs are trained on science that is likely outdated by the time they become professors, rewarded to churn out as many grants as possible, and never given a day of managerial training. Switching to industry after my PhD was a breath of fresh air.
The biggest predictor of intelligence in the animal kingdom is the surface area of brain tissue, not size. You get more surface area by having more folds and bumps (sulci and gyri) on your brain.
Brains are made of neurons and neurons are organized into two types of brain tissue - gray and white matter. Gray matter is where the cell bodies are located, and white matter is where all their connections (axons) are located. Gray matter tends to be found on the surface of all these sulci and gyri, while white matter is located underneath this layer. More surface area = more efficiently connected brain cells.
I don’t know of any literature looking at human intelligence related to folds and bumps, but that’s not what I studied in graduate school. You have to be careful when looking at the older literature on intelligence because it was fairly prejudiced and designed to prove old ideas of race theory.
Academic publishing was definitely a contributing factor to why I left academic research.
I also believe we should incentive peer-review. Maybe every researcher should be evaluated on how many articles they peer-review each year, relative to the amount they publish. I knew some researchers who would publish dozens of articles every year, would peer-review zero of them, and then complain about poor quality peer review.
+1 for Endeavour, apart from the unfortunate update of legacy NVIDIA drivers (10xx series of cards losing mainline support) this December I’ve had 0 issues
This just in, hearing aids are woke?
Here’s the original press release for anyone interested: https://newsroom.heart.org/news/long-term-use-of-melatonin-supplements-to-support-sleep-may-have-negative-health-effects
The most important sentence: “They were matched with peers in the database who also had insomnia but never had melatonin recorded in their health records. People were excluded from the analysis if they had previously been diagnosed with heart failure or had been prescribed other sleep medications.” There are a few other sentences describing how well the control group was matched. I think it was a well-designed study.
I think there is still a risk of bias present, though, because people who decide to take melatonin might have more severe insomnia compared to people who just decide to just “live with it” and are not using sleep aids.
The next step should be a randomized clinical trial looking at heart failure rate in patients with insomnia dosed with melatonin versus placebo and/or a different medication. Until then, correlation does not mean causation. I don’t think such a study will be done in the US because melatonin is considered a dietary supplement and is not subject to the same degree of regulation as medicine. Maybe in the UK, since melatonin is prescription only?
Tiny castle or big banana?
It gets better - the local minor league baseball team is called the Florence Y’alls. And their mascot is a water tower. It’s so Midwest.
Jimthew.
By the time I finished graduate school, reddit was dead so I never bothered getting verified on the Science subreddits. It was a bummer!
I’ll be the pedant no one asked for - the sodium and potassium channels in the neuron respond to voltage changes in the membrane, so the author isn’t wrong.
Action potentials are generated when dendritic (input) channels bind with neurotransmitters like glutamate and GABA released by the axon terminal (output) of the pre-synapse cell. When these channels open, the let in ions like Calcium, Sodium, and Chloride.
These ions change the electric potential across the cell membrane, once this passes a key threshold, the sodium channels in the rest of the cell open up and generate an action potential. It’s driven by ions with electric charge (electrochemical).
Not quite, an iron lung replaces a dysfunctional organ. I’m saying we can already grow neurons onto circuits, and it’s difficult (not impossible) to implant neurons into a body. I don’t easily see how these bio-engineered neurons make those processes easier.
Credentials: I published in this field, but I don’t have time to read the entire paper right now.
This is exciting work. Based on the key highlights, it sounds like their work focuses on how plausible it is to construct the bio-artificial neuron, and they have done so with great success.
What I would like to learn about is what advantages this technology has compared to just cultivating neurons on a microelectrode array. Are the artificial cells easier to maintain? Do they interface with electrodes without developing glial scarring like our brains do? Can they bio-engineer special proteins (e.g. optogenetic channels) easier in these cells than in mouse lines?
The discussion section is fairly anemic. The authors say this will “spearhead” additional development but I was disappointed the authors didn’t clarify what will be additionally developed.
Until these advantages are spelled out, it feels like we’re re-invented the biological wheel. We already have cells that can integrate and fire at low voltages. They’re called neurons. Why did we need artificial ones?
I was about that age when I was gifted a microscope. No idea if you can still find them that cheap, though
This happened with an academic conference (physics iirc). A professor was asked to speak and she submitted a headshot for use in their advertising, but the conference wanted a different aspect ratio. Rather than crop the image, the materials designer asked ChatGPT to expand the photo to the correct size. It gave the professor a low cut shirt, and no one at the conference company noticed until the promotional materials were distributed and the professor contacted them.
Fold-tober sounds fun! I’d get into it
Hey, there’s another one on the forums, they actually fixed their system: https://forum.endeavouros.com/t/a-start-job-is-running-for-dev-disk-uui-running-for-5min/80783