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Motor control refers to the process by which the nervous system coordinates the muscle and limbs to achieve a desired movement or set of actions. This includes the ability to anticipate, adjust and respond to deviations from the desired action.
Wide-field one-photon calcium imaging from new-world primates uncovers a small patch in the medial premotor areas uniquely representing reward expectancy in the frontoparietal cortex.
Wu and colleagues developed movement-triggered brain stimulation that increased beta-band brain activity and improved retention of a newly learned motor adaptation.
How cerebellar circuits control precise paw placement during locomotion remains unclear. Here, the authors show that cerebellar neurons encode paw-specific step transitions and adjust their activity with learning, supporting precise motor control.
Electrical stimulation of the motor thalamus is often thought to impair speech. Here, the authors show that low-frequency stimulation instead preserves and can improve speech and swallowing motor functions after brain injury.
Current speech brain-computer interfaces (BCIs) rely on patient-specific decoding approaches. Here, the authors show that patient-specific data can be aligned to a shared space that preserves speech information, enabling cross-patient speech BCIs.
Motor imagery brain-computer interfaces are promising neurotechnologies but limited by slow user learning and unstable decoder adaptation. Here, the authors develop a novel sensory-guided joint learning framework that coordinates subject learning and decoder adaptation to improve BCI acquisition.
Training on brain–computer interfaces is shown to be markedly improved by using real-time reinforcement feedback instead of relying only on sensory feedback, which can be impaired in users of these devices.
We developed a thin, flexible microelectrode array that can be slid through a small slit in the skull onto the brain surface. We showed that this minimally invasive system records and stimulates neural activity across broad cortical areas, demonstrating high-resolution brain–computer interfacing in animals and in human pilot studies.