https://sourceforge.net/p/cyberunits/wiki/2026-03-16T08:31:13.226000ZRecent changes to wiki2026-03-16T08:31:13.226000Z2026-03-16T08:31:13.226000ZJohannes W. Dietrichhttps://sourceforge.net/u/jwdietrich/https://sourceforge.net94db35977a451019a4c4aadda6f8b6ffe9c0bd60

<div class="markdown_content"><pre>--- v9 +++ v10 @@ -4,7 +4,7 @@ 1. Dietrich JW. [Signal Storage in Metabolic Pathways: The ASIA Element.](http://www.kybernetiknet.de/ausgabe3/dietrich20001228.pdf) kybernetiknet. 2000;1(3, 2000):1-9. -+ Dietrich, J. W. and B. O. Boehm (2006). Equilibrium behaviour of feedback-coupled physiological saturation kinetics. In: Cybernetics and Systems 2006. R. Trappl (Hrsg). Vienna, Austrian Society for Cybernetic Studies. 1: 269-74. doi:[10.13140/2.1.2400.2568](https://doi.org/10.13140/2.1.2400.2568} ++ Dietrich, J. W. and B. O. Boehm (2006). Equilibrium behaviour of feedback-coupled physiological saturation kinetics. In: Cybernetics and Systems 2006. R. Trappl (Hrsg). Vienna, Austrian Society for Cybernetic Studies. 1: 269-74. doi:[10.13140/2.1.2400.2568](https://doi.org/10.13140/2.1.2400.2568) + Dietrich JW, Boehm BO: Die MiMe-NoCoDI-Plattform: Ein Ansatz für die Modellierung biologischer Regelkreise. GMS - German Medical Science 2015(60. Jahrestagung der GMDS e.V.): DocAbstr. 284. </pre> </div>

2026-03-16T08:30:48.855000Z2026-03-16T08:30:48.855000ZJohannes W. Dietrichhttps://sourceforge.net/u/jwdietrich/https://sourceforge.net566cbc28d8999611c26aafe1f68d3b2cb7cdac7c

<div class="markdown_content"><pre>--- v8 +++ v9 @@ -4,7 +4,7 @@ 1. Dietrich JW. [Signal Storage in Metabolic Pathways: The ASIA Element.](http://www.kybernetiknet.de/ausgabe3/dietrich20001228.pdf) kybernetiknet. 2000;1(3, 2000):1-9. -+ Dietrich, J. W. and B. O. Boehm (2006). [Equilibrium behaviour of feedback-coupled physiological saturation kinetics.](http://homepage.ruhr-uni-bochum.de/Johannes.Dietrich/pub/emcsr2006_269.pdf) In: Cybernetics and Systems 2006. R. Trappl (Hrsg). Vienna, Austrian Society for Cybernetic Studies. 1: 269-74. ++ Dietrich, J. W. and B. O. Boehm (2006). Equilibrium behaviour of feedback-coupled physiological saturation kinetics. In: Cybernetics and Systems 2006. R. Trappl (Hrsg). Vienna, Austrian Society for Cybernetic Studies. 1: 269-74. doi:[10.13140/2.1.2400.2568](https://doi.org/10.13140/2.1.2400.2568} + Dietrich JW, Boehm BO: Die MiMe-NoCoDI-Plattform: Ein Ansatz für die Modellierung biologischer Regelkreise. GMS - German Medical Science 2015(60. Jahrestagung der GMDS e.V.): DocAbstr. 284. </pre> </div>

2026-01-29T16:40:14.387000Z2026-01-29T16:40:14.387000ZJohannes W. Dietrichhttps://sourceforge.net/u/jwdietrich/https://sourceforge.net0fde5ce75fe49cf0ddbaff798b5560a42be423bc

<div class="markdown_content"><pre>--- v7 +++ v8 @@ -14,7 +14,7 @@ + Dietrich JW, P4-Endokrinologie – Kybernetische Perspektiven eines neuen Ansatzes, Leibniz Online, Dez. 2024, doi: [10.53201/leibnizonline54](https://doi.org/10.53201/leibnizonline54). -##### Publications on procects using CyberUnits Bricks: ##### +##### Publications on projects that are based on CyberUnits Bricks: ##### 1. Dietrich JW, Dasgupta R, Anoop S, Jebasingh F, Kurian ME, Inbakumari M, Boehm BO, Thomas N. SPINA Carb: a simple mathematical model supporting fast in-vivo estimation of insulin sensitivity and beta cell function. Sci Rep. 2022 Oct 21;12(1):17659. doi: [10.1038/s41598-022-22531-3](https://doi.org/10.1038/s41598-022-22531-3). PMID: [36271244](https://pubmed.ncbi.nlm.nih.gov/36271244/); PMCID: [PMC9587026](https://pmc.ncbi.nlm.nih.gov/articles/PMC9587026/); LIVIVO permalink [M36271244](https://www.livivo.de/doc/M36271244). </pre> </div>

2026-01-29T16:33:33.503000Z2026-01-29T16:33:33.503000ZJohannes W. Dietrichhttps://sourceforge.net/u/jwdietrich/https://sourceforge.net4cb54dfb34c36dba73ebb50de150327fd8956cac

<div class="markdown_content"><pre>--- v6 +++ v7 @@ -12,7 +12,7 @@ + Dietrich JW, Siegmar N, Hojjati JR, Gardt O, Boehm BO. CyberUnits Bricks: An Implementation Study of a Class Library for Simulating Nonlinear Biological Feedback Loops. ADCAIJ: Advances in Distributed Computing and Artificial Intelligence Journal, 2024 Aug 27;13(1):e31762. doi: [10.14201/adcaij.31762](https://doi.org/10.14201/adcaij.31762). -+ Dietrich JW, „P4-Endokrinologie – Kybernetische Perspektiven eines neuen Ansatzes“, Leibniz Online, Dez. 2024, doi: [10.53201/leibnizonline54](https://doi.org/10.53201/leibnizonline54). ++ Dietrich JW, P4-Endokrinologie – Kybernetische Perspektiven eines neuen Ansatzes, Leibniz Online, Dez. 2024, doi: [10.53201/leibnizonline54](https://doi.org/10.53201/leibnizonline54). ##### Publications on procects using CyberUnits Bricks: ##### </pre> </div>

2026-01-29T16:33:09.355000Z2026-01-29T16:33:09.355000ZJohannes W. Dietrichhttps://sourceforge.net/u/jwdietrich/https://sourceforge.netdf8b4dfc250c666f65266f4ad7c45b1a22e1ad4a

<div class="markdown_content"><pre>--- v5 +++ v6 @@ -12,6 +12,8 @@ + Dietrich JW, Siegmar N, Hojjati JR, Gardt O, Boehm BO. CyberUnits Bricks: An Implementation Study of a Class Library for Simulating Nonlinear Biological Feedback Loops. ADCAIJ: Advances in Distributed Computing and Artificial Intelligence Journal, 2024 Aug 27;13(1):e31762. doi: [10.14201/adcaij.31762](https://doi.org/10.14201/adcaij.31762). ++ Dietrich JW, „P4-Endokrinologie – Kybernetische Perspektiven eines neuen Ansatzes“, Leibniz Online, Dez. 2024, doi: [10.53201/leibnizonline54](https://doi.org/10.53201/leibnizonline54). + ##### Publications on procects using CyberUnits Bricks: ##### 1. Dietrich JW, Dasgupta R, Anoop S, Jebasingh F, Kurian ME, Inbakumari M, Boehm BO, Thomas N. SPINA Carb: a simple mathematical model supporting fast in-vivo estimation of insulin sensitivity and beta cell function. Sci Rep. 2022 Oct 21;12(1):17659. doi: [10.1038/s41598-022-22531-3](https://doi.org/10.1038/s41598-022-22531-3). PMID: [36271244](https://pubmed.ncbi.nlm.nih.gov/36271244/); PMCID: [PMC9587026](https://pmc.ncbi.nlm.nih.gov/articles/PMC9587026/); LIVIVO permalink [M36271244](https://www.livivo.de/doc/M36271244). </pre> </div>

2026-01-29T16:28:40.023000Z2026-01-29T16:28:40.023000ZJohannes W. Dietrichhttps://sourceforge.net/u/jwdietrich/https://sourceforge.netdb8be502567c2ea152b3db403815019bf4861896

<div class="markdown_content"><pre>--- v4 +++ v5 @@ -14,6 +14,6 @@ ##### Publications on procects using CyberUnits Bricks: ##### -1. Dietrich JW, Dasgupta R, Anoop S, Jebasingh F, Kurian ME, Inbakumari M, Boehm BO, Thomas N. SPINA Carb: a simple mathematical model supporting fast in-vivo estimation of insulin sensitivity and beta cell function. Sci Rep. 2022 Oct 21;12(1):17659. doi: [10.1038/s41598-022-22531-3](https://doi.org/10.1038/s41598-022-22531-3). PMID: [36271244](https://pubmed.ncbi.nlm.nih.gov/36271244/); PMCID: [PMC9587026](https://pmc.ncbi.nlm.nih.gov/articles/PMC9587026/). +1. Dietrich JW, Dasgupta R, Anoop S, Jebasingh F, Kurian ME, Inbakumari M, Boehm BO, Thomas N. SPINA Carb: a simple mathematical model supporting fast in-vivo estimation of insulin sensitivity and beta cell function. Sci Rep. 2022 Oct 21;12(1):17659. doi: [10.1038/s41598-022-22531-3](https://doi.org/10.1038/s41598-022-22531-3). PMID: [36271244](https://pubmed.ncbi.nlm.nih.gov/36271244/); PMCID: [PMC9587026](https://pmc.ncbi.nlm.nih.gov/articles/PMC9587026/); LIVIVO permalink [M36271244](https://www.livivo.de/doc/M36271244). -+ Dietrich JW, Abood A, Dasgupta R, Anoop S, Jebasingh FK, Spurgeon R, Thomas N, Boehm BO. A novel simple disposition index (SPINA-DI) from fasting insulin and glucose concentration as a robust measure of carbohydrate homeostasis. J Diabetes. 2024 Sep;16(9):e13525. doi: [10.1111/1753-0407.13525](https://doi.org/10.1111/1753-0407.13525). Epub 2024 Jan 2. PMID: [38169110](https://pubmed.ncbi.nlm.nih.gov/38169110/); PMCID: [PMC11418405](https://pmc.ncbi.nlm.nih.gov/articles/PMC11418405/). ++ Dietrich JW, Abood A, Dasgupta R, Anoop S, Jebasingh FK, Spurgeon R, Thomas N, Boehm BO. A novel simple disposition index (SPINA-DI) from fasting insulin and glucose concentration as a robust measure of carbohydrate homeostasis. J Diabetes. 2024 Sep;16(9):e13525. doi: [10.1111/1753-0407.13525](https://doi.org/10.1111/1753-0407.13525). Epub 2024 Jan 2. PMID: [38169110](https://pubmed.ncbi.nlm.nih.gov/38169110/); PMCID: [PMC11418405](https://pmc.ncbi.nlm.nih.gov/articles/PMC11418405/); LIVIVO permalink [M38169110](https://www.livivo.de/doc/M38169110). </pre> </div>

2026-01-29T16:24:30.277000Z2026-01-29T16:24:30.277000ZJohannes W. Dietrichhttps://sourceforge.net/u/jwdietrich/https://sourceforge.net9488031d0b292e62cddae3f403a2c547d9da5206

<div class="markdown_content"><pre>--- v3 +++ v4 @@ -12,7 +12,7 @@ + Dietrich JW, Siegmar N, Hojjati JR, Gardt O, Boehm BO. CyberUnits Bricks: An Implementation Study of a Class Library for Simulating Nonlinear Biological Feedback Loops. ADCAIJ: Advances in Distributed Computing and Artificial Intelligence Journal, 2024 Aug 27;13(1):e31762. doi: [10.14201/adcaij.31762](https://doi.org/10.14201/adcaij.31762). -##### Publication on procects using CyberUnits Bricks: ##### +##### Publications on procects using CyberUnits Bricks: ##### 1. Dietrich JW, Dasgupta R, Anoop S, Jebasingh F, Kurian ME, Inbakumari M, Boehm BO, Thomas N. SPINA Carb: a simple mathematical model supporting fast in-vivo estimation of insulin sensitivity and beta cell function. Sci Rep. 2022 Oct 21;12(1):17659. doi: [10.1038/s41598-022-22531-3](https://doi.org/10.1038/s41598-022-22531-3). PMID: [36271244](https://pubmed.ncbi.nlm.nih.gov/36271244/); PMCID: [PMC9587026](https://pmc.ncbi.nlm.nih.gov/articles/PMC9587026/). </pre> </div>

2026-01-29T16:24:14.133000Z2026-01-29T16:24:14.133000ZJohannes W. Dietrichhttps://sourceforge.net/u/jwdietrich/https://sourceforge.net240e68e81a9e721e5cc7b95dacd731a644cdccd5

<div class="markdown_content"><pre>--- v2 +++ v3 @@ -11,3 +11,9 @@ + Dietrich JW. A Methodology for Vertical Translation Between Molecular and Organismal Level in Biological Feedback Loops. bioRxiv 2021.09.20.461028; doi: [10.1101/2021.09.20.461028](https://doi.org/10.1101/2021.09.20.461028) + Dietrich JW, Siegmar N, Hojjati JR, Gardt O, Boehm BO. CyberUnits Bricks: An Implementation Study of a Class Library for Simulating Nonlinear Biological Feedback Loops. ADCAIJ: Advances in Distributed Computing and Artificial Intelligence Journal, 2024 Aug 27;13(1):e31762. doi: [10.14201/adcaij.31762](https://doi.org/10.14201/adcaij.31762). + +##### Publication on procects using CyberUnits Bricks: ##### + +1. Dietrich JW, Dasgupta R, Anoop S, Jebasingh F, Kurian ME, Inbakumari M, Boehm BO, Thomas N. SPINA Carb: a simple mathematical model supporting fast in-vivo estimation of insulin sensitivity and beta cell function. Sci Rep. 2022 Oct 21;12(1):17659. doi: [10.1038/s41598-022-22531-3](https://doi.org/10.1038/s41598-022-22531-3). PMID: [36271244](https://pubmed.ncbi.nlm.nih.gov/36271244/); PMCID: [PMC9587026](https://pmc.ncbi.nlm.nih.gov/articles/PMC9587026/). + ++ Dietrich JW, Abood A, Dasgupta R, Anoop S, Jebasingh FK, Spurgeon R, Thomas N, Boehm BO. A novel simple disposition index (SPINA-DI) from fasting insulin and glucose concentration as a robust measure of carbohydrate homeostasis. J Diabetes. 2024 Sep;16(9):e13525. doi: [10.1111/1753-0407.13525](https://doi.org/10.1111/1753-0407.13525). Epub 2024 Jan 2. PMID: [38169110](https://pubmed.ncbi.nlm.nih.gov/38169110/); PMCID: [PMC11418405](https://pmc.ncbi.nlm.nih.gov/articles/PMC11418405/). </pre> </div>

2026-01-26T00:36:41.631000Z2026-01-26T00:36:41.631000ZJohannes W. Dietrichhttps://sourceforge.net/u/jwdietrich/https://sourceforge.net07f956a2dcece13b7535ecef3e127681c144ad1d

<div class="markdown_content"><pre>--- v14 +++ v15 @@ -3,7 +3,7 @@ ### Bricks ### -**Milestone 2.1 (Foudre) +**Milestone 2.1 (Foudre)** *Multiple new features* </pre> </div>

2026-01-26T00:36:11.312000Z2026-01-26T00:36:11.312000ZJohannes W. Dietrichhttps://sourceforge.net/u/jwdietrich/https://sourceforge.net1ad0c8f871bb1f0e600fcb5ce1e87b96466cace7

<div class="markdown_content"><pre>--- v13 +++ v14 @@ -3,11 +3,17 @@ ### Bricks ### +**Milestone 2.1 (Foudre) + +*Multiple new features* + +Bricks 2.1.0: Major upgrade introducing a proportional-integral (PI) block, a scaling option for systems diagrams, a solver unit that facilitates the solution of algebraic equations and extended functionality of ASIA elements, as well as additional demo programs and bug fixes (SVN commits r126 to r165, 26-I-2026). + **Milestone 2.0 (Escorpión)** *Multiple new features* -Bricks 2.0.0: Major upgrade implementing a plethora of new features (including but not limited to a model class, test signals and tools for signal analysis) as well as important bug fixes (SVN commits r111 to r124, 17-VI-2023) +Bricks 2.0.0: Major upgrade implementing a plethora of new features (including but not limited to a model class, test signals and tools for signal analysis) as well as important bug fixes (SVN commits r111 to r124, 17-VI-2023). **Milestone 1.1 (Dendron)** </pre> </div>